The alarming growth of the antibiotic-resistant superbugs has created a demand for sensors that can investigate antibiotics and their modes of action. The label-free detection of the antibiotic vancomycin binding to mucopeptides on cantilever arrays, with 10 nM sensitivity and at clinically relevant concentrations in blood serum, could lead to improved biosensors and a better understanding of antibiotic drug action in bacteria.
- Joseph Wafula Ndieyira
- Moyu Watari
- Rachel A. McKendry
