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Advanced filters: Author: Trine Strandgaard Clear advanced filters

An integrated multi-omics analysis identifies prognostic molecular subtypes of non-muscle-invasive bladder cancer

Multiple molecular profiling methods are required to study urothelial non-muscle-invasive bladder cancer (NMIBC) due to its heterogeneity. Here the authors integrate multi-omics data of 834 NMIBC patients, identifying a molecular subgroup associated with multiple alterations and worse outcomes.

Sia Viborg Lindskrog
Frederik Prip
Lars Dyrskjøt
ResearchOpen Access16 Apr 2021
Nature Communications

Volume: 12, P: 1-18
Comprehensive genomic characterization of early-stage bladder cancer

A genomic and transcriptomic analysis of nonmuscle-invasive bladder cancer identifies four molecular subtypes, and associates whole-genome duplication and immune exhaustion with tumor progression.

Frederik Prip
Philippe Lamy
Lars Dyrskjøt
ResearchOpen Access03 Jan 2025
Nature Genetics

Volume: 57, P: 115-125
Circulating tumour DNA and circulating tumour cells in bladder cancer — from discovery to clinical implementation

In this Review, the authors provide an overview of circulating tumour DNA and circulating tumour cells as potential biomarkers to provide therapeutic guidance and optimize disease surveillance in bladder cancer. Challenges associated with these biomarkers and future perspectives for clinical implementation are also discussed.

Sia V. Lindskrog
Trine Strandgaard
Lars Dyrskjøt
Reviews15 Apr 2025
Nature Reviews Urology

Volume: 22, P: 590-608

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