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Showing 1–2 of 2 results
Advanced filters: Author: Tristan Lerbs Clear advanced filters

  • Fibroblast contributions to lung fibrosis and in particular their crosstalk with immune cells in the lung are incompletely understood. Here, the authors show an overall immune suppressive environment transcriptionally controlled and maintained by fibroblasts in lung fibrosis with possible therapeutic implications.

    • Lu Cui
    • Shih-Yu Chen
    • Gerlinde Wernig
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-14

  • Abdominal adhesions are a common cause of bowel obstruction, but knowledge regarding adhesion biology and anti-adhesion therapies remains limited. Here the authors report a systematic analysis of mouse and human adhesion tissues demonstrating that visceral fibroblast JUN and associated PDGFRA expression promote adhesions, and JUN suppression can prevent adhesion formation.

    • Deshka S. Foster
    • Clement D. Marshall
    • Michael T. Longaker
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-18