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Advanced filters: Author: Tzer Han Tan Clear advanced filters

Light-induced cortical excitability reveals programmable shape dynamics in starfish oocytes

Optogenetically induced chemo-mechanical excitations are used to drive and study shape deformations in starfish oocytes. Understanding and eventually controlling such waves is important for the development of synthetic cells.

Jinghui Liu
Tom Burkart
Nikta Fakhri
Research24 Mar 2025
Nature Physics

Volume: 21, P: 846-855
Topological turbulence in the membrane of a living cell

Activity in certain living systems can lead to swirling flows akin to turbulence. Here, the authors connect the dynamics of topological defects in starfish oocyte membranes to vortex dynamics in 2D Bose–Einstein condensates.

Tzer Han Tan
Jinghui Liu
Nikta Fakhri
Research23 Mar 2020
Nature Physics

Volume: 16, P: 657-662
Odd dynamics of living chiral crystals

Experiments show that swimming starfish embryos spontaneously assemble into large chiral crystals that exhibit self-sustained chiral oscillations and unconventional deformation responses characteristic of odd elastic materials.

Tzer Han Tan
Alexander Mietke
Nikta Fakhri
Research13 Jul 2022
Nature

Volume: 607, P: 287-293
A hierarchy of protein patterns robustly decodes cell shape information

Cells exploit protein pattern formation to perform key processes, and do so while undergoing major shape changes. Experiments and theory together reveal a shape-adaptation mechanism capable of controlling protein dynamics even as the cell deforms.

Manon C. Wigbers
Tzer Han Tan
Nikta Fakhri
Research15 Feb 2021
Nature Physics

Volume: 17, P: 578-584
Super-resolution imaging of fluorescently labeled, endogenous RNA Polymerase II in living cells with CRISPR/Cas9-mediated gene editing

Won-Ki Cho
Namrata Jayanth
Ibrahim I. Cissé
ResearchOpen Access26 Oct 2016
Scientific Reports

Volume: 6, P: 1-8