ARLNC1 is a newly discovered lncRNA that is induced by androgen receptor (AR) and maintains AR signaling by stabilizing the AR transcript. Knockdown of ARLNC1 suppresses AR expression, AR signaling and prostate cancer growth in vitro and in vivo.
- Yajia Zhang
- Sethuramasundaram Pitchiaya
- Arul M. Chinnaiyan