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Advanced filters: Author: Uma Rajarajacholan Clear advanced filters

  • Glycogen Storage Disease 1a (Gsd1a) is an inherited disorder caused by glucose 6-phosphatase (G6Pase-α) deficiency and characterized by hypoglycaemia and high risk of liver cancer. Here the authors develop a mRNA-based G6Pase-α delivery therapy that is efficacious and safe in a mouse model of GSD1a.

    • Jingsong Cao
    • Minjung Choi
    • Paloma H. Giangrande
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-14