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Showing 1–2 of 2 results
Advanced filters: Author: Umberto Restuccia Clear advanced filters

  • Tpr nucleoporin is known to be essential for nuclear transport and mitosis processes. Here the authors explore the link between Tpr and genome instability providing insights into the role of Tpr in safeguarding cells from RNA-mediated replication stress.

    • Martin Kosar
    • Michele Giannattasio
    • Marco Foiani
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-18

  • The nucleus is a mechanically stiff organelle of the cell and the DNA damage response protein ATR can localize to the nuclear envelope upon mechanical stress. Here, the authors show that ATR may contribute to the integrity of the nuclear envelope and may play a role in cell migration.

    • Gururaj Rao Kidiyoor
    • Qingsen Li
    • Marco Foiani
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-16