Nature Search

A miniaturized mode-of-action profiling platform enables high throughput characterization of the molecular and cellular dynamics of EZH2 inhibition

Lilia Falkenstern
Victoria Georgi
Amaury Fernández-Montalván
ResearchOpen Access19 Jan 2024
Scientific Reports

Volume: 14, P: 1-21
Global chromatin profiling reveals NSD2 mutations in pediatric acute lymphoblastic leukemia

Frank Stegmeier, Levi Garraway and colleagues apply a targeted mass spectrometry approach that measures level of histone modifications and identify a recurrent p.E1099K variant in NSD2 in acute lymphoblastic leukemia. When ectopically expressed in a cancer cell line, this variant promotes transformation.

Jacob D Jaffe
Yan Wang
Frank Stegmeier
Research29 Sept 2013
Nature Genetics

Volume: 45, P: 1386-1391
Dynamically tuned non-classical light emission from atomic defects in hexagonal boron nitride

Quantum photonics investigates how a controlled number of photons can be used to achieve information processing beyond classical constraints. Here, the authors use optically active defects in hexagonal boron nitride as way to achieve control of photon emission using surface acoustic waves.

Snežana Lazić
André Espinha
Herko P. van der Meulen
ResearchOpen Access17 Sept 2019
Communications Physics

Volume: 2, P: 1-8
Development of secondary mutations in wild-type and mutant EZH2 alleles cooperates to confer resistance to EZH2 inhibitors

V Gibaja
F Shen
H M Chan
ResearchOpen Access20 Apr 2015
Oncogene

Volume: 35, P: 558-566

Quick links

Search

Filter By:

A miniaturized mode-of-action profiling platform enables high throughput characterization of the molecular and cellular dynamics of EZH2 inhibition

Global chromatin profiling reveals NSD2 mutations in pediatric acute lymphoblastic leukemia

Dynamically tuned non-classical light emission from atomic defects in hexagonal boron nitride

Development of secondary mutations in wild-type and mutant EZH2 alleles cooperates to confer resistance to EZH2 inhibitors

Search

Quick links