Transcriptomics is widely used to identify functional and developmental states of T cells and their genetically engineered therapeutic counterparts, such as CAR-T cells. Here authors show that by looking at epigenetic markers in human CD8 + T cells and CAR-T cells, properties and quality of these cells, which are not obvious from gene expression analysis, could be accurately described.
- S. Fiorenza
- Y. Zheng
- C. J. Turtle
