Research has highlighted the importance of the stroma in pancreatic cancer, in particular the role of complex interactions between cancer and stromal cells. A new study describes a novel mechanism by which stromal pathways can be modulated to inhibit tumour growth. The findings support the concept that a multipronged therapeutic approach targeting pancreatic cancer cells and cancer stroma could improve clinical outcomes for this disease.
- Minoti V. Apte
- Jeremy S. Wilson