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Showing 1–4 of 4 results
Advanced filters: Author: Valentina Abbiento Clear advanced filters

  • Omicron strains of SARS-CoV-2 have displayed high transmissibility and immunological escape to antibody responses derived from natural infection and vaccination. Here the authors compare the antibody response to vaccination and natural infection, assessing neutralisation after vaccine doses and analyse the repertoire of such responses.

    • Emanuele Andreano
    • Ida Paciello
    • Rino Rappuoli
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-9

  • Here, Andreano and Paciello et al. show, at single cell level, the functional and genetic characteristics underlying the Omicron BA.1 and BA.2 cross-protective antibody response in naïve and previously infected COVID-19 vaccinees.

    • Emanuele Andreano
    • Ida Paciello
    • Rino Rappuoli
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-8

  • SARS-CoV-2 vaccines and infection induce antibody responses but the evolution of subsequent variants has resulted in the development of escape mutants. Here the authors characterise, at single cell level, the antibody response in donors after a third dose of SARS-CoV-2 mRNA vaccination and show difference in breadth, neutralisation and molecular signature according to the vaccination regimen used.

    • Emanuele Andreano
    • Ida Paciello
    • Rino Rappuoli
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-9

  • Single-cell-level analysis of memory B cells and their response to vaccination against all SARS-CoV-2 variants of concern in individuals who either had or had not been previously exposed to the virus.

    • Emanuele Andreano
    • Ida Paciello
    • Rino Rappuoli
    ResearchOpen Access
    Nature
    Volume: 600, P: 530-535