Preeclampsia is a leading cause of morbidity and mortality in pregnancy and has multiple causes. Here the authors examine how changes in the gut microbiota alter pregnancy outcome and show changes in fetal reabsorption along with reduction in placental NK cell IFN-γ production accompanied by perturbation of placental carbohydrate metabolism.
- Silvia Giugliano
- Andrea Gatti
- Maria Rescigno