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Showing 1–4 of 4 results
Advanced filters: Author: Valentina Goldfarb Clear advanced filters

  • NMR resonances of backbone nuclei have been assigned for >95% of the residues in oxidized, substrate-free, perdeuterated 13C/15N-labelled MurB (347 residues). A novel approach utilizing minimum chemical shift changes was employed to localize the NADP+ binding site on MurB.

    • Bennett T. Farmer II
    • Keith L. Constantine
    • Luciano Mueller
    Correspondence
    Nature Structural Biology
    Volume: 3, P: 995-997

  • Clay is thought to have played a part in the origin of life. Here, the authors show that layered double hydroxides, a type of clay little studied despite its presumed prevalence on the early Earth, can facilitate the formation of small proteins.

    • Valentina Erastova
    • Matteo T. Degiacomi
    • H. Chris Greenwell
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-9

  • Triclosan (TCS), an antimicrobial agent commonly found in consumer products, has been reported to exacerbates colitis in animal models. Here, using in vitro and in vivo approaches, the authors show that gut bacterial enzymes can drive the metabolic activation and gut toxicity of TCS, highlighting an important role of intestinal microbial factors in the complex etiology of colitis.

    • Jianan Zhang
    • Morgan E. Walker
    • Guodong Zhang
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-14