Nature Search

Clonal dynamics towards the development of venetoclax resistance in chronic lymphocytic leukemia

BCL2-inhibitor venetoclax is used to treat relapsed/refractory chronic lymphocytic leukemia (CLL). Here, the authors show the clonal dynamics towards venetoclax resistance by performing whole-exome sequencing of 8 CLL patients undergoing venetoclax treatment.

Carmen D. Herling
Nima Abedpour
Martin Peifer
ResearchOpen Access20 Feb 2018
Nature Communications

Volume: 9, P: 1-8
Dermatologist-like explainable AI enhances melanoma diagnosis accuracy: eye-tracking study

Artificial intelligence (AI) system is known to improve dermatologists’ diagnostic accuracy for melanoma. This group applies the eye-tracking technology on dermatologists when diagnosing dermoscopic images of melanomas and reports improved balanced diagnostic accuracy when using an X(explainable) AI system comparing to the standard one.

Tirtha Chanda
Sarah Haggenmueller
Titus J. Brinker
ResearchOpen Access21 May 2025
Nature Communications

Volume: 16, P: 1-10
Adjuvant dendritic cell therapy in stage IIIB/C melanoma: the MIND-DC randomized phase III trial

Immunotherapy using dendritic cell (DC)-based vaccination has been exploited in the clinic for cancer treatment. Here the authors report the results of a randomized, placebo-controlled, phase 3 trial of adjuvant blood-derived DC cell-based therapy in patients with stage IIIB and IIIC melanoma.

Kalijn F. Bol
Gerty Schreibelt
I. Jolanda M. de Vries
ResearchOpen Access23 Feb 2024
Nature Communications

Volume: 15, P: 1-10
Upper environmental pCO₂ drives sensitivity to ocean acidification in marine invertebrates

The authors link the effects of pCO₂ on marine invertebrates to the localized pCO₂ conditions of their coastal habitats. They show that responses depend on the deviation from the locally experienced upper pCO₂ level, highlighting the importance of small-scale variability and adaptation.

Cristian A. Vargas
L. Antonio Cuevas
Sam Dupont
Research03 Feb 2022
Nature Climate Change

Volume: 12, P: 200-207
Allogeneic Hematopoietic Cell Transplantation in Advanced Systemic Mastocytosis: A retrospective analysis of the DRST and GREM registries

Johannes Lübke
Deborah Christen
Jens Panse
ResearchOpen Access06 Mar 2024
Leukemia

Volume: 38, P: 810-821
Linking social preferences and ocean acidification impacts in mussel aquaculture

Valeska A. San Martin
Stefan Gelcich
Cristian A. Vargas
ResearchOpen Access18 Mar 2019
Scientific Reports

Volume: 9, P: 1-9
Attention, cognitive control and motivation in ADHD: Linking event-related brain potentials and DNA methylation patterns in boys at early school age

Hartmut Heinrich
Juliane Grunitz
Anna Eichler
ResearchOpen Access19 Jun 2017
Scientific Reports

Volume: 7, P: 1-12

Search

Filter By:

Clonal dynamics towards the development of venetoclax resistance in chronic lymphocytic leukemia

Dermatologist-like explainable AI enhances melanoma diagnosis accuracy: eye-tracking study

Adjuvant dendritic cell therapy in stage IIIB/C melanoma: the MIND-DC randomized phase III trial

Upper environmental pCO2 drives sensitivity to ocean acidification in marine invertebrates

Allogeneic Hematopoietic Cell Transplantation in Advanced Systemic Mastocytosis: A retrospective analysis of the DRST and GREM registries

Linking social preferences and ocean acidification impacts in mussel aquaculture

Attention, cognitive control and motivation in ADHD: Linking event-related brain potentials and DNA methylation patterns in boys at early school age

Search

Quick links

Upper environmental pCO₂ drives sensitivity to ocean acidification in marine invertebrates