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Showing 1–3 of 3 results
Advanced filters: Author: Vanessa Niebauer Clear advanced filters
  • Although chromatin remodelers have been shown to align nucleosome arrays to barriers and to generate spacing regularity among nucleosomes within arrays, it has remained unclear how the distance to barrier and the spacing length are determined in absolute terms. Here, the authors reveal that remodelers contain a ‘ruler’ element that sets remodeler-specific alignment and spacing distances when generating nucleosome arrays.

    • Elisa Oberbeckmann
    • Vanessa Niebauer
    • Philipp Korber
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-17
  • DNA sequence preferences or statistical positioning of histones has not explained genomic patterns of nucleosome organisation in vivo. Here, the authors establish DNA shape/mechanics as key elements that have evolved together with binding sites of DNA sequence-specific barriers so that such information directs nucleosome positioning by chromatin remodelers.

    • Elisa Oberbeckmann
    • Nils Krietenstein
    • Sebastian Eustermann
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-19