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Showing 1–2 of 2 results
Advanced filters: Author: Vasyl Bondarenko Clear advanced filters

  • The intracellular domain (ICD) of Cys-loop receptors mediates many of their functions, but no complete structure of a Cys-loop receptor ICD is available to date. Here, the authors combine NMR and ESR spectroscopy to determine the full-length ICD structures of the human α7 nicotinic acetylcholine receptor (α7nAChR).

    • Vasyl Bondarenko
    • Marta M. Wells
    • Pei Tang
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-9

  • Characterization of the interaction between PTH and its G-protein-coupled receptor, PTHR, shows conformational changes coupled to residues interacting with His9, which helps position the PTH N terminus at the PTHR transmembrane domain to facilitate β-arrestin coupling.

    • Lisa J. Clark
    • James Krieger
    • Jean-Pierre Vilardaga
    Research
    Nature Chemical Biology
    Volume: 16, P: 1096-1104