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Showing 1–6 of 6 results
Advanced filters: Author: Veerasak Srisuknimit Clear advanced filters

  • Members of the DUF368-containing and DedA transmembrane protein families have conditional roles in undecaprenyl phosphate translocation in Gram-negative and Gram-positive bacteria and may have a widely conserved function in the biogenesis of microbial cell surface glycopolymers.

    • Brandon Sit
    • Veerasak Srisuknimit
    • Matthew K. Waldor
    ResearchOpen Access
    Nature
    Volume: 613, P: 721-728

  • A tRNA modification, named 2-aminovaleramididine (ava2C), has been discovered in plant organelles and bacteria. Structural analysis shows specific codon recognition by this modification, highlighting the evolutionary diversity of the essential tRNA modifications.

    • Kenjyo Miyauchi
    • Satoshi Kimura
    • Tsutomu Suzuki
    ResearchOpen Access
    Nature Chemical Biology
    Volume: 21, P: 522-531

  • C-to-Ψ conversion is a previously uncharacterized form of base editing. Here, the authors describe how the TrcP enzyme catalyzes this process in a stepwise fashion and how this editing process is controlled by a network of modifications and nutrient availability to optimize translation efficiency.

    • Satoshi Kimura
    • Veerasak Srisuknimit
    • Matthew K. Waldor
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-15

  • Use of a combined Tn-seq and machine-learning approach for predicting mechanisms and targets of antibiotic action in Staphylococcus aureus shows that the natural product lysocin E (LysE) binds Lipid II on the cell surface and damages the membrane.

    • Marina Santiago
    • Wonsik Lee
    • Suzanne Walker
    Research
    Nature Chemical Biology
    Volume: 14, P: 601-608

  • Evolutionary coupling-enabled molecular replacement determination of the structure of Thermus thermophilus RodA reveals a highly conserved cavity in its transmembrane domain, and mutagenesis experiments in Bacillus subtilis and Escherichia coli show that perturbation of this cavity abolishes RodA function.

    • Megan Sjodt
    • Kelly Brock
    • Andrew C. Kruse
    Research
    Nature
    Volume: 556, P: 118-121