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Nature Cancer (2)
Oncogenesis (1)

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Showing 1–3 of 3 results

Advanced filters: Author: Venu Thatikonda Clear advanced filters

Co-targeting SOS1 enhances the antitumor effects of KRAS^G12C inhibitors by addressing intrinsic and acquired resistance

Hofmann and colleagues describe the mechanism underlying the therapeutic benefit of combinatorial use of SOS1 and KRAS-G12C inhibitors in the context of KRAS-G12C mutant-driven lung and colorectal cancer.

Venu Thatikonda
Hengyu Lyu
Marco H. Hofmann
ResearchOpen Access05 Aug 2024
Nature Cancer

Volume: 5, P: 1352-1370
Comprehensive analysis of mutational signatures reveals distinct patterns and molecular processes across 27 pediatric cancers

Jäger and colleagues analyze single-base substitution and indel mutational signatures across 27 pediatric cancer types, revealing marked differences in mutational patterns compared with adult cancers and insights into underlying molecular mechanisms.

Venu Thatikonda
S. M. Ashiqul Islam
Natalie Jäger
ResearchOpen Access26 Jan 2023
Nature Cancer

Volume: 4, P: 276-289
A subtype of cancer-associated fibroblasts with lower expression of alpha-smooth muscle actin suppresses stemness through BMP4 in oral carcinoma

Ankit Kumar Patel
Kavya Vipparthi
Sandeep Singh
ResearchOpen Access05 Oct 2018
Oncogenesis

Volume: 7, P: 1-15