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Showing 1–2 of 2 results
Advanced filters: Author: Veronica Valadares Clear advanced filters

  • Correlating aromatic carbons attached to fluorine with meta-position hydrogens in fluorine-labelled phenylalanines can yield two-dimensional correlations with narrow linewidths in large proteins. Adapting phenylalanine-tRNA synthetase increases the incorporation rate, while expanding the genetic code enables site-specific incorporation of fluorinated phenylalanine. The resulting HCF-transverse relaxation-optimized spectroscopy can illuminate protein dynamics and drive multiplexed drug discovery campaigns.

    • Andras Boeszoermenyi
    • Denitsa L. Radeva
    • Haribabu Arthanari
    Research
    Nature Chemistry
    Volume: 17, P: 835-846

  • The authors report genome-wide data from 34 ancient individuals spanning the Holocene, from what is now Brazil, illuminating connections and disjoints between Sambaqui shellmound societies and preceding and later peoples.

    • Tiago Ferraz
    • Ximena Suarez Villagran
    • Cosimo Posth
    ResearchOpen Access
    Nature Ecology & Evolution
    Volume: 7, P: 1315-1330