Drs2, a phospholipid translocase involved in transport from the trans-Golgi network, is shown to be a new effector of PtdIns(4)P (phosphatidylinositol 4-phosphate). Binding to PtdIns(4)P and to the GTPase exchange factor ARF–GEF, a regulator of Golgi transport, stimulates Drs2 activity.
- Paramasivam Natarajan
- Ke Liu
- Todd R. Graham