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Showing 1–6 of 6 results

Advanced filters: Author: Vincent Stroobant Clear advanced filters

Evidence for a tumoral immune resistance mechanism based on tryptophan degradation by indoleamine 2,3-dioxygenase

Catherine Uyttenhove
Luc Pilotte
Benoît J Van den Eynde
Research21 Sept 2003
Nature Medicine

Volume: 9, P: 1269-1274
Production of an antigenic peptide by insulin-degrading enzyme

Most antigenic peptides presented by MHC class I are produced by the proteasome. Van den Eynde and co-workers show that a MAGE-A3–derived peptide is produced directly by the cytosolic metallopeptidase IDE.

Nicolas Parmentier
Vincent Stroobant
Benoît J Van den Eynde
Research04 Apr 2010
Nature Immunology

Volume: 11, P: 449-454
A conserved phosphatase destroys toxic glycolytic side products in mammals and yeast

The glycolytic enzymes GAPDH and pyruvate kinase produce 4-phosphoerythronate and 2-phospho-L-lactate, which block metabolic flux. A newly identified conserved metabolic repair enzyme, phosphoglycolate phosphatase, eliminates these side products.

François Collard
Francesca Baldin
Guido T Bommer
Research13 Jun 2016
Nature Chemical Biology

Volume: 12, P: 601-607
PBP-A, a cyanobacterial dd-peptidase with high specificity for amidated muropeptides, exhibits pH-dependent promiscuous activity harmful to Escherichia coli

Gol Mohammad Dorrazehi
Matthias Winkle
Patrice Soumillion
ResearchOpen Access18 Jun 2024
Scientific Reports

Volume: 14, P: 1-16
Efficiency of the four proteasome subtypes to degrade ubiquitinated or oxidized proteins

Joanna Abi Habib
Etienne De Plaen
Benoit J. Van den Eynde
ResearchOpen Access25 Sept 2020
Scientific Reports

Volume: 10, P: 1-17
Knock-in of murine Calr del52 induces essential thrombocythemia with slow-rising dominance in mice and reveals key role of Calr exon 9 in cardiac development

Thomas Balligand
Younes Achouri
Stefan N. Constantinescu
Research30 Aug 2019
Leukemia

Volume: 34, P: 510-521