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Clinical validation of an AI-based pathology tool for scoring of metabolic dysfunction-associated steatohepatitis

In a prospective, regulatory-grade study of assistance to pathologists in MASH histology scoring, AIM-MASH-assisted reads by expert MASH pathologists were superior to unassisted reads and decreased inter-reader variability.

Hanna Pulaski
Stephen A. Harrison
Katy E. Wack
ResearchOpen Access04 Nov 2024
Nature Medicine

Volume: 31, P: 315-322
Association of artificial intelligence-powered and manual quantification of programmed death-ligand 1 (PD-L1) expression with outcomes in patients treated with nivolumab ± ipilimumab

Vipul Baxi
George Lee
Michael Montalto
ResearchOpen Access15 Jul 2022
Modern Pathology

Volume: 35, P: 1529-1539
Image analysis reveals molecularly distinct patterns of TILs in NSCLC associated with treatment outcome

Ruiwen Ding
Prateek Prasanna
Anant Madabhushi
ResearchOpen Access03 Jun 2022
npj Precision Oncology

Volume: 6, P: 1-15
Elevated serum interleukin-8 is associated with enhanced intratumor neutrophils and reduced clinical benefit of immune-checkpoint inhibitors

In a retrospective analysis of data from four phase 3 clinical trials, elevated baseline serum IL-8 levels were associated with worse clinical outcomes in patients with multiple tumor types treated with anti-PD-1 monotherapy or anti-PD-1 and anti-CTLA-4 combinatorial therapy.

Kurt A. Schalper
Michael Carleton
Ignacio Melero
Research11 May 2020
Nature Medicine

Volume: 26, P: 688-692
Deep computational image analysis of immune cell niches reveals treatment-specific outcome associations in lung cancer

Cristian Barrera
Germán Corredor
Anant Madabhushi
ResearchOpen Access01 Jun 2023
npj Precision Oncology

Volume: 7, P: 1-17
Digital pathology and artificial intelligence in translational medicine and clinical practice

Vipul Baxi
Robin Edwards
Saurabh Saha
ReviewsOpen Access05 Oct 2021
Modern Pathology

Volume: 35, P: 23-32

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Clinical validation of an AI-based pathology tool for scoring of metabolic dysfunction-associated steatohepatitis

Association of artificial intelligence-powered and manual quantification of programmed death-ligand 1 (PD-L1) expression with outcomes in patients treated with nivolumab ± ipilimumab

Image analysis reveals molecularly distinct patterns of TILs in NSCLC associated with treatment outcome

Elevated serum interleukin-8 is associated with enhanced intratumor neutrophils and reduced clinical benefit of immune-checkpoint inhibitors

Deep computational image analysis of immune cell niches reveals treatment-specific outcome associations in lung cancer

Digital pathology and artificial intelligence in translational medicine and clinical practice

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