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Showing 151–200 of 532 results
Advanced filters: Author: Vivien How Clear advanced filters

  • The grant deadline approaches but budget details are still missing. Experienced budget-makers share how they manage budgets and the ‘boom–bust’ cycle.

    • Vivien Marx
    News
    Nature Methods
    Volume: 21, P: 152

  • Sometimes their queer identity is one that people set apart from their science identity. Others find unique ways to integrate multiple facets of their identity.

    • Vivien Marx
    News
    Nature Methods
    Volume: 21, P: 924

  • Researchers roll up their sleeves for the work ahead in the noncoding RNA field.

    • Vivien Marx
    Special Features
    Nature Methods
    Volume: 19, P: 1171-1174

  • Sometimes a drug causes a tumour to completely recede, but only in a tiny percentage of people. Scientists want to decipher such outlier responses for the benefit of all patients.

    • Vivien Marx
    Special Features
    Nature
    Volume: 520, P: 389-393

  • Coherent quantum control of a single 123Sb nucleus using electric fields produced within a silicon nanoelectronic device is demonstrated experimentally, validating a concept predicted theoretically in 1961.

    • Serwan Asaad
    • Vincent Mourik
    • Andrea Morello
    Research
    Nature
    Volume: 579, P: 205-209

  • It's been a long wait for nanopore sequencing technology. Over 1,000 labs are testing the first commercial device and publishing results. Researchers tell Nature Methods about their experiences putting these early instruments through their paces. And more technology is in the works.

    • Vivien Marx
    Special Features
    Nature Methods
    Volume: 12, P: 1015-1018

  • Some researchers run and hide from the task of authenticating cell lines. A few simple steps save time and money.

    • Vivien Marx
    Special Features
    Nature Methods
    Volume: 11, P: 483-488

  • Analysis of 97,691 high-coverage human blood DNA-derived whole-genome sequences enabled simultaneous identification of germline and somatic mutations that predispose individuals to clonal expansion of haematopoietic stem cells, indicating that both inherited and acquired mutations are linked to age-related cancers and coronary heart disease.

    • Alexander G. Bick
    • Joshua S. Weinstock
    • Pradeep Natarajan
    Research
    Nature
    Volume: 586, P: 763-768

  • The Human Microbiome Project Consortium reports the first results of their analysis of microbial communities from distinct, clinically relevant body habitats in a human cohort; the insights into the microbial communities of a healthy population lay foundations for future exploration of the epidemiology, ecology and translational applications of the human microbiome.

    • Curtis Huttenhower
    • Dirk Gevers
    • Owen White
    ResearchOpen Access
    Nature
    Volume: 486, P: 207-214

  • Stabilization of DNA quadruplex structures (G4) is lethal for cells with a compromised DNA repair pathway. Here, the authors show that CX-5461, a small molecule in clinical trials as RNA polymerase inhibitor, has G4-stablization properties and can be repurposed to target DNA repair-defective cancers cells.

    • Hong Xu
    • Marco Di Antonio
    • Samuel Aparicio
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-18

  • Magnetic quasiparticles in a doped quantum magnet are shown to be well suited for realizing and exploring the ‘glassy’ states that are predicted to emerge for interacting bosons in the presence of disorder.

    • Rong Yu
    • Liang Yin
    • Tommaso Roscilde
    Research
    Nature
    Volume: 489, P: 379-384

  • At some meetings, one gets to know all attendees. But at large conferences, that’s rather impossible. Some first-time attendees share how they navigated the sizable Society for Neuroscience annual meeting.

    • Vivien Marx
    News
    Nature Methods
    Volume: 21, P: 2197

  • Quantum computing promises plenty, such as how it can massively accelerate some bioinformatics calculations.

    • Vivien Marx
    Special Features
    Nature Methods
    Volume: 18, P: 715-719

  • Beyond the well-known pantheon of model organisms are others. A shift is underway to level the playing field.

    • Vivien Marx
    Special Features
    Nature Methods
    Volume: 18, P: 235-239

  • Quantum computers will require a large network of coherent qubits, connected in a noise-resilient way. Tosi et al. present a design for a quantum processor based on electron-nuclear spins in silicon, with electrical control and coupling schemes that simplify qubit fabrication and operation.

    • Guilherme Tosi
    • Fahd A. Mohiyaddin
    • Andrea Morello
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-11

  • A map of the male worm's posterior nervous system offers some surprises.

    • Vivien Marx
    Research Highlights
    Nature Methods
    Volume: 9, P: 947

  • Researchers recapitulate in the lab how an infectious parasite gains its ferociousness.

    • Vivien Marx
    Research Highlights
    Nature Methods
    Volume: 10, P: 107

  • Moving and sorting cells with sound are a few of the possible applications for this no-contact technique.

    • Vivien Marx
    Special Features
    Nature Methods
    Volume: 12, P: 41-44

  • Machine learning and imaging show what the dreaming brain sees.

    • Vivien Marx
    Research Highlights
    Nature Methods
    Volume: 10, P: 462

  • Blinking and photobleaching of fluorophores cause challenges in a whole range of imaging experiments. Here are some ways researchers are approaching fluorophore photostability.

    • Vivien Marx
    Special Features
    Nature Methods
    Volume: 12, P: 187-190

  • Both tried-and-true and new assays are helping labs to assess methylation at particular loci and from single cells.

    • Vivien Marx
    Special Features
    Nature Methods
    Volume: 13, P: 119-122

  • The menu of maturing, diversifying methods calls for careful selections in experimental design.

    • Vivien Marx
    Special Features
    Nature Methods
    Volume: 9, P: 1055-1059

  • Cloud computing can help busy genomics labs. But researchers will want to be cautious shoppers as they scan the skies for the cloud best suited to their needs.

    • Vivien Marx
    Special Features
    Nature Methods
    Volume: 10, P: 941-945

  • Labs can generate neurons from pluripotent stem cells to study basic biology and to model disease. Protocols are getting more robust, and labs add personal preferences.

    • Vivien Marx
    Special Features
    Nature Methods
    Volume: 13, P: 617-622

  • Tools are emerging to help labs trawl for sequences that reveal microbial strains and their functional potential in deep pools of metagenomic data.

    • Vivien Marx
    Special Features
    Nature Methods
    Volume: 13, P: 401-404

  • Trial, error and the art of optimizing 'molecular rulers' that sense molecules or interactions.

    • Vivien Marx
    Special Features
    Nature Methods
    Volume: 14, P: 949-953

  • Large-scale phenotyping is generating much data that geneticists can harness. Amid the excitement about the possibilities, there are some points of caution.

    • Vivien Marx
    Special Features
    Nature Methods
    Volume: 12, P: 711-714

  • To those who seek transcriptomic information at high resolution, scale and throughput, single-cell RNA sequencing brings the data. Scientists share tips and future plans as they reflect on the method’s rise to stardom.

    • Vivien Marx
    Special Features
    Nature Methods
    Volume: 21, P: 750-753

  • Early-career scientists shared some of their plans, hopes and dreams about being a principal investigator at the 2024 annual meeting of the International Society for Stem Cell Research.

    • Vivien Marx
    News
    Nature Methods
    Volume: 21, P: 1570

  • In China, the first children with germline-edited genomes are growing up. How might their edited genomes affect their lives?

    • Vivien Marx
    News
    Nature Biotechnology
    Volume: 39, P: 1486-1490

  • How computational neuroanatomy, vintage gear and fado fit together.

    • Vivien Marx
    News
    Nature Methods
    Volume: 18, P: 325

  • With strategies for reproducibility and quality control, scientists seek to cultivate better practices in quantitative PCR experiments.

    • Vivien Marx
    Special Features
    Nature Methods
    Volume: 10, P: 391-395

  • Instruments for studying microbes under biological containment cannot be readily removed from labs for servicing. A US facility is finding ways around that problem.

    • Vivien Marx
    Special Features
    Nature
    Volume: 505, P: 437-441

  • Cell lines are better. Mice are better. Beyond disagreement about model systems and even passionate discord at times, new strategies help to explore the middle ground so models might better approximate human biology.

    • Vivien Marx
    Special Features
    Nature Methods
    Volume: 11, P: 617-620

  • Imaging and microscopy technology advances in leaps and bounds. To address accumulated pain points, academics and companies are making headway on standards.

    • Vivien Marx
    Special Features
    Nature Methods
    Volume: 19, P: 784-788

  • A maturing open hardware and open-source software movement seeks to expand DIY light-sheet microscopy.

    • Vivien Marx
    Special Features
    Nature Methods
    Volume: 13, P: 979-982

  • A tool that combines free satellite imagery, a machine learning model, and building footprint data enables the interactive mapping and assessment of war-related damage at scale, with the potential to adjust the confidence interval to the case at hand.

    • Olivier Dietrich
    • Torben Peters
    • Jan Dirk Wegner
    ResearchOpen Access
    Communications Earth & Environment
    Volume: 6, P: 1-10

  • Mass spectrometrists travel top down, middle down and bottom up to study post-translational modifications on proteins and their biological functions.

    • Vivien Marx
    Special Features
    Nature Methods
    Volume: 10, P: 201-204

  • Many possibilities for parsing cancer emerge when labs combine gene editing and screens. And RNAi retains its spot in the menu of options.

    • Vivien Marx
    Special Features
    Nature Methods
    Volume: 14, P: 343-346

  • Sequencing technology drives microbiology and gives researchers new reasons to draw on classic techniques.

    • Vivien Marx
    Special Features
    Nature Methods
    Volume: 14, P: 37-40