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Showing 1–23 of 23 results
Advanced filters: Author: Vivien Matthias Clear advanced filters

  • A comparison of the repertoire of SARS-CoV-2-specific epitopes targeted by T cells induced by vaccination or natural infection reveals that T cells predominantly target non-spike epitopes in convalescent individuals, while there is a broader spike-specific CD8+ T-cell response in vaccinees. Despite differences in T-cell response, the targeted T-cell epitopes were conserved between the wild-type and Omicron variants in both groups.

    • Julia Lang-Meli
    • Hendrik Luxenburger
    • Christoph Neumann-Haefelin
    ResearchOpen Access
    Nature Microbiology
    Volume: 7, P: 675-679

  • Vaccines induce beneficial immunity for COVID-19, but immune waning prompts boosting vaccination. Here, the authors show that a third, boosting dose of COVID-19 mRNA vaccine induces transient CD8 + T effector cell response while conserving the CD8 memory T cell pool, thereby permitting reactivation of spike-specific CD8 + T cells upon breakthrough infection or 4th vaccination.

    • Matthias Reinscheid
    • Hendrik Luxenburger
    • Maike Hofmann
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-11

  • By building engineered microenvironments, scientists probe the many talents of stem cells.

    • Vivien Marx
    Special Features
    Nature Methods
    Volume: 10, P: 111-115

  • In microfluidics, sharing is hard. But practitioners are exploring new ways to share designs, devices and experience.

    • Vivien Marx
    Special Features
    Nature Methods
    Volume: 15, P: 167-170

  • Developing new methods takes passion and a penchant for risk-taking.

    • Vivien Marx
    News
    Nature Methods
    Volume: 21, P: 1766

  • A cascaded hard X-ray self-seeding system is demonstrated at the European X-ray free-electron laser. The setup enables millijoule-level pulses in the photon energy range of 6–14 keV at the rate of ten trains per second, with each train including hundreds of pulses arriving at a megahertz repetition rate.

    • Shan Liu
    • Christian Grech
    • Gianluca Geloni
    ResearchOpen Access
    Nature Photonics
    Volume: 17, P: 984-991

  • With strategies for reproducibility and quality control, scientists seek to cultivate better practices in quantitative PCR experiments.

    • Vivien Marx
    Special Features
    Nature Methods
    Volume: 10, P: 391-395

  • A case–control study investigating the causes of recent cases of acute hepatitis of unknown aetiology in 32 children identifies an association between adeno-associated virus infection and host genetics in disease susceptibility.

    • Antonia Ho
    • Richard Orton
    • Emma C. Thomson
    Research
    Nature
    Volume: 617, P: 555-563

  • Building a sustainable open source toolbox to track social behavior and how to get in the zone.

    • Vivien Marx
    News
    Nature Methods
    Volume: 19, P: 373

  • Analyzing cleared tissue with a deep-learning pipeline, and why dreaming is good for science.

    • Vivien Marx
    News
    Nature Methods
    Volume: 17, P: 357

  • How to make cells spill their metabolic guts in high-throughput, and why work does not feel like work.

    • Vivien Marx
    News
    Nature Methods
    Volume: 12, P: 997

  • Infection with SARS-COV-2 can result in self-limited upper airway infection or progress to a more systemic inflammatory condition including pneumonic COVID-19. Here the authors utilise a multi-omics approach to interrogate the immune response of patients with self-limiting upper respiratory SARS-CoV-2 infection and reveal a temporal immune trajectory they associate with viral containment and restriction from pneumonic progressive disease.

    • Kami Pekayvaz
    • Alexander Leunig
    • Leo Nicolai
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-21

  • The influence of X chromosome genetic variation on blood lipids and coronary heart disease (CHD) is not well understood. Here, the authors analyse X chromosome sequencing data across 65,322 multi-ancestry individuals, identifying associations of the Xq23 locus with lipid changes and reduced risk of CHD and diabetes mellitus.

    • Pradeep Natarajan
    • Akhil Pampana
    • Gina M. Peloso
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-14

  • Coaxing ancient DNA to reveal its history delivers surprises and even improves ways of working with badly damaged present-day DNA.

    • Vivien Marx
    Special Features
    Nature Methods
    Volume: 14, P: 771-774

  • Hundreds of researchers collaborate on maps of the human body and the subcellular realm. As they scout out their next mapping expeditions, they take stock of atlas-making.

    • Vivien Marx
    News
    Nature Methods
    Volume: 21, P: 2203-2208