The authors present a statistical and computational framework to identify allele-specific variants, i.e., single nucleotide variants exhibiting allele-specificity (allelic imbalance) in any type of omics assay. Application of this framework to thousands of datasets yields an atlas of chromatin altering variants in diverse cell types.
- Andrey Buyan
- Georgy Meshcheryakov
- Ivan V. Kulakovskiy
