Laliotis et al. examine the role of the AKT3-phoshorylated RNA
processing factor IWS1 and the IWS1 phosphorylation-dependent alternative splicing
of U2AF2 in lung adenocarcinoma cells. The alternatively spliced variant of
U2AF2 regulates the nuclear export of
CAR-Epositive intronless mRNAs, including those encoding Type I interferons.
- Georgios I. Laliotis
- Adam D. Kenney
- Philip N. Tsichlis
