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Advanced filters: Author: Walison Nunes da Silva Clear advanced filters

  • Here the authors screen different lipid nanoparticle (LNP) formulations for intramuscular delivery of plasmid DNA and uptake by antigen-presenting cells. The lead LNP exhibits immunogenicity and protection in small animal models that is comparable to approved SARS-CoV-2 mRNA vaccine formulations.

    • Lays Cordeiro Guimaraes
    • Pedro Augusto Carvalho Costa
    • Pedro Pires Goulart Guimaraes
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-19