Catalytic asymmetric hydroboration of unsaturated bonds is the most straightforward method for the construction of chiral organoboron compounds but enantioselective hydroboration of allenes is challenging. Here, the authors report a cobalt-catalyzed asymmetric dihydroboration of allenes using a ligand relay strategy with two simple ligands to obtain chiral 1,4-diboronate products.
- Yaqin Lei
- Yu Kong
- Wanxiang Zhao