The little elongation complex (LEC) has been implicated in the regulation of Pol II-transcribed snRNA genes. Here, the authors show that MED26 recruits the LEC to a subset of Pol II-transcribed snRNAgenes through its N terminus, entailing a TAF7 to LEC switch that facilitates the transition from initiation to elongation.
- Hidehisa Takahashi
- Ichigaku Takigawa
- Shigetsugu Hatakeyama
