Two papers in this issue show that dynein-binding proteins may regulate the G1–S transition through an effect on cilia. Nde1, a known partner of dynein light chain LC8, controls ciliary length in vitro and in zebrafish, and influences the G1–S progression. The phosphorylation of Tctex1, a dynein light chain, modulates cilia length and accelerates G1–S, thereby regulating proliferation–differentiation decisions in the developing mouse neocortex.
