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Showing 1–4 of 4 results

Advanced filters: Author: Wei-Lin Qiu Clear advanced filters

POH1 deubiquitylates and stabilizes E2F1 to promote tumour formation

The transcription factor E2F1 controls the expression of multiple genes and is frequently overactivated in cancer. Here, the authors show that E2F1 is deubiquitinated by POH1 and that this enhances the role of E2F1 in cell survival, and contributes to the pathogenesis of liver cancer.

Boshi Wang
Aihui Ma
Yongzhong Liu
ResearchOpen Access29 Oct 2015
Nature Communications

Volume: 6, P: 1-15
Sequential progenitor states mark the generation of pancreatic endocrine lineages in mice and humans

Xin-Xin Yu
Wei-Lin Qiu
Cheng-Ran Xu
Research10 Mar 2021
Cell Research

Volume: 31, P: 886-903
Thyrostimulin-TSHR signaling promotes the proliferation of NIH:OVCAR-3 ovarian cancer cells via trans-regulation of the EGFR pathway

Wei-Lin Huang
Zhongyou Li
Ching-Wei Luo
ResearchOpen Access07 Jun 2016
Scientific Reports

Volume: 6, P: 1-13
Single-cell patterning and axis characterization in the murine and human definitive endoderm

Lin-Chen Li
Xin Wang
Cheng-Ran Xu
Research26 Oct 2020
Cell Research

Volume: 31, P: 326-344