During DNA recombination, two DNA molecules become covalently linked in a four-way structure known as a Holliday junction, which stay connected until the structure is dissolved by the protein resolvase. Although structures of a naked Holliday junction have been obtained, it has been difficult to solve the structure of resolvase sitting in a Holliday junction. This is one of two papers that use two different phage resolvases to solve the structure of resolvase sitting in a Holliday junction.
- Christian Biertümpfel
- Wei Yang
- Dietrich Suck