Nature Search

Non-contact ultrasound to assist laser additive manufacturing

This manuscript presents a non-contact ultrasonic system for large-scale additive manufacturing, where the low-intensity ultrasound without cavitation refines grains via dendrite fragmentation through acoustic streaming and Marangoni-driven melt flow.

Jiasen Han
Shuhao Wang
Xin Lin
ResearchOpen Access15 Aug 2025
Nature Communications

Volume: 16, P: 1-13
Identification of multiple genomic alterations and prediction of neoantigens from circulating tumor cells at the single-cell level

This study introduces Uni-C, a single-cell method to map chromatin structure and genomic alterations in circulating tumor cells, enabling detection of genomic variants and neoantigen prediction to advance early diagnosis and therapeutic strategies.

Xiaochen Gao
Xinyu Li
Da Lin
ResearchOpen Access26 Jul 2025
Nature Communications

Volume: 16, P: 1-15
PIEZO1 mechanically regulates the antitumour cytotoxicity of T lymphocytes

Blocking the mechanical sensor PIEZO1 in cytotoxic T lymphocytes strengthens their traction forces and augments their cytotoxicity against tumour cells.

Ruiyang Pang
Weihao Sun
Yuying Liu
Research21 Mar 2024
Nature Biomedical Engineering

Volume: 8, P: 1162-1176
A selection pressure landscape for 870 human polygenic traits

Song et al. quantify the signal of natural selection on 870 complex traits in European individuals, finding that 88% of traits showed signals of selection in the past 3,000 years, including traits related to pigmentation, body shape and food intake.

Weichen Song
Yueqi Shi
Guan Ning Lin
Research15 Nov 2021
Nature Human Behaviour

Volume: 5, P: 1731-1743
Improving prime editing with an endogenous small RNA-binding protein

Genome-scale genetic screens identify the small RNA-binding protein La as a strong mediator of prime editing.

Jun Yan
Paul Oyler-Castrillo
Britt Adamson
ResearchOpen Access03 Apr 2024
Nature

Volume: 628, P: 639-647
A genome-wide association study identifies six novel risk loci for primary biliary cholangitis

Primary biliary cholangitis is an autoimmune liver disease. Here, the authors show that variants in interleukin genes which potentially deregulate their expression are associated with this condition, and suggest that the IL21 signalling pathway may have a role in disease aetiology.

Fang Qiu
Ruqi Tang
Xiong Ma
ResearchOpen Access20 Apr 2017
Nature Communications

Volume: 8, P: 1-8
Automated synthesis of prexasertib and derivatives enabled by continuous-flow solid-phase synthesis

Although strategies for the automated assembly of compounds of pharmaceutical relevance is a growing field of research, the synthesis of small-molecule pharmacophores remains a predominantly manual process. Now, an automated six-step synthesis of prexasertib is achieved by multistep solid-phase chemistry in a continuous-flow fashion using a chemical recipe file that enables automated scaffold modification through both early and late-stage diversification.

Chenguang Liu
Jiaxun Xie
Jie Wu
Research19 Apr 2021
Nature Chemistry

Volume: 13, P: 451-457
Enhancing ophthalmology medical record management with multi-modal knowledge graphs

Weihao Gao
Fuju Rong
Lan Ma
ResearchOpen Access05 Oct 2024
Scientific Reports

Volume: 14, P: 1-12
Limits on the luminance of dark matter from xenon recoil data

A direct search for effective electromagnetic interactions between dark matter and xenon nuclei that produce a recoil of the latter is carried out and the first constraint on charge radius of dark matter is derived.

Xuyang Ning
Abdusalam Abdukerim
Yubo Zhou
Research17 May 2023
Nature

Volume: 618, P: 47-50
Machine tool FEM model correction assisted by dynamic evolution sequence

Weihao Lin
Peng Zhong
Xuanlong Wu
ResearchOpen Access29 May 2025
Scientific Reports

Volume: 15, P: 1-14
AMD-SD: An Optical Coherence Tomography Image Dataset for wet AMD Lesions Segmentation

Yunwei Hu
Yundi Gao
Guodong Li
ResearchOpen Access18 Sept 2024
Scientific Data

Volume: 11, P: 1-8
Long noncoding RNA CRCMSL suppresses tumor invasive and metastasis in colorectal carcinoma through nucleocytoplasmic shuttling of HMGB2

Qinrui Han
Lijun Xu
Liang Zhao
Research21 Dec 2018
Oncogene

Volume: 38, P: 3019-3032
NIT1 suppresses tumour proliferation by activating the TGFβ1–Smad2/3 signalling pathway in colorectal cancer

Chun Lin
Jianming Zhang
Xuenong Li
ResearchOpen Access15 Feb 2018
Cell Death & Disease

Volume: 9, P: 1-12
Small GTPase RAB6 deficiency promotes alveolar progenitor cell renewal and attenuates PM2.5-induced lung injury and fibrosis

Lawei Yang
Gang Liu
Xuenong Li
ResearchOpen Access04 Oct 2020
Cell Death & Disease

Volume: 11, P: 1-17
Bioactive secondary metabolites from the deep-sea derived fungus Aspergillus sp. SCSIO 41029

Weihao Chen
Chunmei Chen
Yonghong Liu
Research27 Oct 2020
The Journal of Antibiotics

Volume: 74, P: 156-159
Specification of the patterning of a ductal tree during branching morphogenesis of the submandibular gland

Janice L. Walker
Weihao Wang
Maria A. Kukuruzinska
ResearchOpen Access11 Jan 2021
Scientific Reports

Volume: 11, P: 1-15

Search

Non-contact ultrasound to assist laser additive manufacturing

Identification of multiple genomic alterations and prediction of neoantigens from circulating tumor cells at the single-cell level

PIEZO1 mechanically regulates the antitumour cytotoxicity of T lymphocytes

A selection pressure landscape for 870 human polygenic traits

Improving prime editing with an endogenous small RNA-binding protein

A genome-wide association study identifies six novel risk loci for primary biliary cholangitis

Automated synthesis of prexasertib and derivatives enabled by continuous-flow solid-phase synthesis

Enhancing ophthalmology medical record management with multi-modal knowledge graphs

Limits on the luminance of dark matter from xenon recoil data

Machine tool FEM model correction assisted by dynamic evolution sequence

AMD-SD: An Optical Coherence Tomography Image Dataset for wet AMD Lesions Segmentation

Long noncoding RNA CRCMSL suppresses tumor invasive and metastasis in colorectal carcinoma through nucleocytoplasmic shuttling of HMGB2

NIT1 suppresses tumour proliferation by activating the TGFβ1–Smad2/3 signalling pathway in colorectal cancer

Small GTPase RAB6 deficiency promotes alveolar progenitor cell renewal and attenuates PM2.5-induced lung injury and fibrosis

Bioactive secondary metabolites from the deep-sea derived fungus Aspergillus sp. SCSIO 41029

Specification of the patterning of a ductal tree during branching morphogenesis of the submandibular gland

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