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Showing 1–4 of 4 results
Advanced filters: Author: Wenbao Qi Clear advanced filters

  • Fluorescence in situ hybridization (FISH) methods with high sensitivity are needed. Here the authors develop multiplex πFISH rainbow to detect a range of biomolecules; they also combine this with the hybridization chain reaction to develop πFISH+ technology for short nucleic acid fragment detection.

    • Yingfeng Tao
    • Xiaoliu Zhou
    • Gang Cao
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-15

  • Jiahao Zhang, Kaixiong Ma, and Bo Li et al. identify a variant of the H9N2 avian influenza virus within the hemagglutinin cleavage site required for viral infection. They show that this variant leads to higher viral replication in cells and more virulent disease in both chickens and mice.

    • Jiahao Zhang
    • Kaixiong Ma
    • Wenbao Qi
    ResearchOpen Access
    Communications Biology
    Volume: 4, P: 1-13

  • The imminent release of tissue atlases combining multichannel microscopy with single-cell sequencing and other omics data from normal and diseased specimens creates an urgent need for data and metadata standards to guide data deposition, curation and release. We describe a Minimum Information about Highly Multiplexed Tissue Imaging (MITI) standard that applies best practices developed for genomics and for other microscopy data to highly multiplexed tissue images and traditional histology.

    • Denis Schapiro
    • Clarence Yapp
    • Peter K. Sorger
    Comments & Opinion
    Nature Methods
    Volume: 19, P: 262-267