The fiber membrane prepared from silk fibroin was modified by polydopamine and grafted the liposomes encapsulated leptin that endow the fiber with vascularization. The fiber membrane was covered with the defect of oral mucosa in rabbits, and leptin was released from the broken liposomes to promote early vascularization and accelerate the regeneration of mucous membrane.
- Chunyu Qian
- Tianwen Xin
- Zili Ge
