Wound repair involves the proper regeneration of the extracellular matrix. When this process goes awry, organ fibrosis results, damaging the organ's function. Now, Michael Zeisberg and his colleagues have uncovered an epigenetic mechanism by which kidney fibrosis occurs, as well as a potential new therapeutic target to prevent it (pages 523–525 and pages 535–543).
- Wibke Bechtel
- Scott McGoohan
- Michael Zeisberg
