Nature Search

γ Interferon induced by S. aureus protein A augments natural killing and ADCC

William J. Catalona
Timothy L. Ratliff
Robert E. McCool
Research07 May 1981
Nature

Volume: 291, P: 77-79
Adenosine Deaminase Deficiency Without Immunodeficiency: Clinical and Metabolic Studies

William Borkowsky
Anne A Gershon
Rochelle Hirschhorn
Research01 Jul 1980
Pediatric Research

Volume: 14, P: 885-889
8q24 genetic variation and comprehensive haplotypes altering familial risk of prostate cancer

Inherited alterations of the 8q24 genomic locus are linked to cancer etiology. Here, the authors investigate hereditary prostate cancer to reveal ancestral risk-altering haplotypes, the sentinel genetic variants optimally predicting risk, and causal mutation candidates.

William D. Dupont
Joan P. Breyer
Jeffrey R. Smith
ResearchOpen Access23 Mar 2020
Nature Communications

Volume: 11, P: 1-12
Utility of the Riskindicator model in screening

Use of a multivariable 'Riskindicator' model might increase the accuracy of screening for clinically significant prostate cancer. Such models, in conjunction with novel biomarkers, hold promise for improving the specificity of screening, and could help to reduce the number of unnecessary biopsies performed in this setting.

Stacy Loeb
William J. Catalona
News & Views01 Apr 2010
Nature Reviews Urology

Volume: 7, P: 184-185
The growing evidence supporting mid-life PSA testing

Serum PSA testing remains controversial as the data regarding its utility are conflicting. However, a recent study adds to the growing body of evidence supporting its usefulness in middle-aged men, especially in the determination of the long-term risk of metastasis and death from prostate cancer.

Daniel Reinhardt
William J. Catalona
News & Views02 Jul 2013
Nature Reviews Urology

Volume: 10, P: 436-438
What is the role of digital rectal examination in men undergoing serial screening of serum PSA levels?

Stacy Loeb
William J Catalona
Comments & Opinion13 Jan 2009
Nature Clinical Practice Urology

Volume: 6, P: 68-69
Early versus delayed intervention for prostate cancer: the case for early intervention

The advent of PSA testing has led to concern that prostate cancer is being over diagnosed with consequent treatment of otherwise harmless tumors, resulting in some centers initiating active monitoring protocols. In this Viewpoint, the authors examine the evidence and argue that early intervention is favorable to active monitoring and delayed treatment.

Stacy Loeb
William J Catalona
Reviews12 Jun 2007
Nature Clinical Practice Urology

Volume: 4, P: 348-349
Common sequence variants on 2p15 and Xp11.22 confer susceptibility to prostate cancer

Julius Gudmundsson
Patrick Sulem
Kari Stefansson
Research10 Feb 2008
Nature Genetics

Volume: 40, P: 281-283
What is the prognostic impact of positive surgical margins in surgically treated prostate cancer?

Stacy Loeb
William J Catalona
Comments & Opinion01 Aug 2006
Nature Clinical Practice Urology

Volume: 3, P: 418-419
High-throughput oncogene mutation profiling in human cancer

Roman K Thomas
Alissa C Baker
Levi A Garraway
Research11 Feb 2007
Nature Genetics

Volume: 39, P: 347-351
RNASEL Arg462Gln variant is implicated in up to 13% of prostate cancer cases

Graham Casey
Phillippa J. Neville
John S. Witte
Research04 Nov 2002
Nature Genetics

Volume: 32, P: 581-583
HOXB13 suppresses de novo lipogenesis through HDAC3-mediated epigenetic reprogramming in prostate cancer

HOXB13 suppresses a lipogenic transcriptional program in prostate cancer (PCa) through HDAC3 recruitment to enhancers. Loss of HOXB13 leads to lipid accumulation in PCa cells, promoting cell motility in vitro and xenograft tumor metastasis in vivo.

Xiaodong Lu
Ka-wing Fong
Jindan Yu
Research25 Apr 2022
Nature Genetics

Volume: 54, P: 670-683
Impaired prostate tumorigenesis in Egr1-deficient mice

Sarki A. Abdulkadir
Zhican Qu
Jeffrey Milbrandt
Research01 Jan 2001
Nature Medicine

Volume: 7, P: 101-107
Genome-wide association study identifies a second prostate cancer susceptibility variant at 8q24

Julius Gudmundsson
Patrick Sulem
Kari Stefansson
Research01 Apr 2007
Nature Genetics

Volume: 39, P: 631-637
A germline variant in the TP53 polyadenylation signal confers cancer susceptibility

Simon Stacey, Kari Stefansson and colleagues show that a germline variant in the TP53 polyadenylation signal is associated with increased risk of basal cell carcinoma and other solid tumors.

Simon N Stacey
Patrick Sulem
Kari Stefansson
Research25 Sept 2011
Nature Genetics

Volume: 43, P: 1098-1103
Germline mutations and sequence variants of the macrophage scavenger receptor 1 gene are associated with prostate cancer risk

Jianfeng Xu
S. Lilly Zheng
Deborah A. Meyers
Research16 Sept 2002
Nature Genetics

Volume: 32, P: 321-325
Sequence variants at the TERT-CLPTM1L locus associate with many cancer types

Following a replicated genome-wide association study for basal cell carcinoma, Thorunn Rafnar and Patrick Sulem and colleagues have identified a locus associated with multiple cancers that contains the telomerase reverse transcriptase gene TERT and the CLPTM1L gene implicated in cisplatin-induced apoptosis.

Thorunn Rafnar
Patrick Sulem
Kari Stefansson
Research18 Jan 2009
Nature Genetics

Volume: 41, P: 221-227
Genome-wide association and replication studies identify four variants associated with prostate cancer susceptibility

Julius Gudmundsson and colleagues report a prostate cancer genome-wide association follow-on study. They report variants at 3q21.3, 8q24.21 and 19q13.2 newly associated to prostate cancer susceptibility and the fine-mapping of the association signal at 11q13.

Julius Gudmundsson
Patrick Sulem
Kari Stefansson
Research20 Sept 2009
Nature Genetics

Volume: 41, P: 1122-1126
A study based on whole-genome sequencing yields a rare variant at 8q24 associated with prostate cancer

Julius Gudmundsson, Kari Stefansson and colleagues identify a low-frequency variant at 8q24 strongly associated with prostate cancer risk. They also confirm association of a recently reported risk variant in HOXB13 in samples from multiple European populations.

Julius Gudmundsson
Patrick Sulem
Kari Stefansson
Research28 Oct 2012
Nature Genetics

Volume: 44, P: 1326-1329
A common variant associated with prostate cancer in European and African populations

Laufey T Amundadottir
Patrick Sulem
Kari Stefansson
Research07 May 2006
Nature Genetics

Volume: 38, P: 652-658
Two variants on chromosome 17 confer prostate cancer risk, and the one in TCF2 protects against type 2 diabetes

Julius Gudmundsson
Patrick Sulem
Kari Stefansson
Research01 Jul 2007
Nature Genetics

Volume: 39, P: 977-983
EPHB4 inhibition activates ER stress to promote immunogenic cell death of prostate cancer cells

Vinay Sagar
Rajita Vatapalli
Sarki A. Abdulkadir
ResearchOpen Access22 Oct 2019
Cell Death & Disease

Volume: 10, P: 1-14
Approaches to urinary detection of prostate cancer

Jillian N. Eskra
Daniel Rabizadeh
Jun Luo
Reviews17 Jan 2019
Prostate Cancer and Prostatic Diseases

Volume: 22, P: 362-381

Search

γ Interferon induced by S. aureus protein A augments natural killing and ADCC

Adenosine Deaminase Deficiency Without Immunodeficiency: Clinical and Metabolic Studies

8q24 genetic variation and comprehensive haplotypes altering familial risk of prostate cancer

Utility of the Riskindicator model in screening

The growing evidence supporting mid-life PSA testing

What is the role of digital rectal examination in men undergoing serial screening of serum PSA levels?

Early versus delayed intervention for prostate cancer: the case for early intervention

Common sequence variants on 2p15 and Xp11.22 confer susceptibility to prostate cancer

What is the prognostic impact of positive surgical margins in surgically treated prostate cancer?

High-throughput oncogene mutation profiling in human cancer

RNASEL Arg462Gln variant is implicated in up to 13% of prostate cancer cases

HOXB13 suppresses de novo lipogenesis through HDAC3-mediated epigenetic reprogramming in prostate cancer

Impaired prostate tumorigenesis in Egr1-deficient mice

Genome-wide association study identifies a second prostate cancer susceptibility variant at 8q24

A germline variant in the TP53 polyadenylation signal confers cancer susceptibility

Germline mutations and sequence variants of the macrophage scavenger receptor 1 gene are associated with prostate cancer risk

Sequence variants at the TERT-CLPTM1L locus associate with many cancer types

Genome-wide association and replication studies identify four variants associated with prostate cancer susceptibility

A study based on whole-genome sequencing yields a rare variant at 8q24 associated with prostate cancer

A common variant associated with prostate cancer in European and African populations

Two variants on chromosome 17 confer prostate cancer risk, and the one in TCF2 protects against type 2 diabetes

EPHB4 inhibition activates ER stress to promote immunogenic cell death of prostate cancer cells

Approaches to urinary detection of prostate cancer

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