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  • An approach called chemo-optical modulation of epigenetically regulated transcription (COMET) combines azobenzene-based photochromic HDAC inhibitors with microprocessor-controlled LED plates to regulate gene expression profiles in a light-dependent manner.

    • Surya A Reis
    • Balaram Ghosh
    • Ralph Mazitschek
    Research
    Nature Chemical Biology
    Volume: 12, P: 317-323