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Showing 1–2 of 2 results
Advanced filters: Author: Wooli Bae Clear advanced filters

  • The typical method for DNA origami fabrication uses thermal annealing of staples to a longer DNA scaffold. Here, the authors present a mechanical method to control the folding pathway, which instead relies on stretching the DNA scaffold in magnetic tweezers, prior to staple incorporation.

    • Wooli Bae
    • Kipom Kim
    • Tae-Young Yoon
    Research
    Nature Communications
    Volume: 5, P: 1-8

  • Information-bearing templates that catalyse the assembly of complex macromolecules are a central motif of natural biochemistry, but their power remains largely unexplored in synthetic contexts. Enzyme-free templating of DNA dimerization has now been demonstrated, using DNA nanotechnology to ensure that the templates are effective information-propagating catalysts.

    • Javier Cabello-Garcia
    • Rakesh Mukherjee
    • Thomas E. Ouldridge
    ResearchOpen Access
    Nature Chemistry
    Volume: 17, P: 1179-1187