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Showing 1–3 of 3 results
Advanced filters: Author: Wren Saylor Clear advanced filters
  • Homologs are paired in Drosophila somatic cells from embryogenesis to adulthood. Using a computational approach for haplotype-resolved Hi-C, the authors reveal highly structured homolog pairing in Drosophila embryos during zygotic genome activation and demonstrate its application to mammalian embryos.

    • Jelena Erceg
    • Jumana AlHaj Abed
    • C.-ting Wu
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-13
  • Trans-homolog interactions, such as homolog pairing, are highly structured and associated with gene function in Drosophila cells. Here, the authors use haplotype-resolved Hi-C to identify genome-wide trans-homolog interactions in a Drosophila hybrid cell line and investigate their patterns and functional roles.

    • Jumana AlHaj Abed
    • Jelena Erceg
    • C.-ting Wu
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-14