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Advanced filters: Author: Wufuer Aini Clear advanced filters
  • The epigenetic regulation in adipocytes during obesity remains poorly understood. Here, the authors demonstrate a negative feedback loop between TET2, a DNA demethylation enzyme, and leptin, an adipokine, in adipocytes, unveiling a compensatory mechanism by which the body counteracts the metabolic dysfunction induced by obesity.

    • Qin Zeng
    • Jianfeng Song
    • Tuo Deng
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-17