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Showing 1–6 of 6 results

Advanced filters: Author: Wuke Wang Clear advanced filters

Discovering CRISPR-Cas system with self-processing pre-crRNA capability by foundation models

Identification of CRISPR-Cas systems by sequence alignment is limited by homolog sequence diversity. Here, the authors develop CHOOSER, and AI framework, for alignment free discovery of CRISPR-Cas systems, including EphcCasλ, which was validated for self-processing and DNA cleavage.

Wenhui Li
Xianyue Jiang
Qi Liu
ResearchOpen Access19 Nov 2024
Nature Communications

Volume: 15, P: 1-14
Author Correction: Discovering CRISPR-Cas system with self-processing pre-crRNA capability by foundation models

Wenhui Li
Xianyue Jiang
Qi Liu
Amendments and CorrectionsOpen Access09 Jan 2025
Nature Communications

Volume: 16, P: 1
Stratospheric ozone loss over the Eurasian continent induced by the polar vortex shift

Climate change can exert a significant effect on the ozone recovery. Here, the authors show that the Arctic polar vortex shift associated with Arctic sea-ice loss could slow down ozone recovery over the Eurasian continent.

Jiankai Zhang
Wenshou Tian
Guang Zeng
ResearchOpen Access15 Jan 2018
Nature Communications

Volume: 9, P: 1-8
Zero-shot prediction of mutation effects with multimodal deep representation learning guides protein engineering

Peng Cheng
Cong Mao
Shengqi Wang
ResearchOpen Access05 Jul 2024
Cell Research

Volume: 34, P: 630-647
Study on the dynamic response characteristics of lining structures in large-section tunnel blasting using JH-2 model analysis

Fengting Li
Ke Wu
Zhongyu Dou
ResearchOpen Access07 May 2024
Scientific Reports

Volume: 14, P: 1-18
Decadal variability of tropical tropopause temperature and its relationship to the Pacific Decadal Oscillation

Wuke Wang
Katja Matthes
Mojib Latif
ResearchOpen Access12 Jul 2016
Scientific Reports

Volume: 6, P: 1-12