Neural mechanisms underlying circadian photoentrainment are not fully understood. Using in vivo two-photon imaging with a GRIN lens, this study reveals a dynamic bi-stable circuit in the suprachiasmatic nucleus that regulates light-driven circadian clock shifts, providing insight into mechanisms of circadian photoentrainment.
- Po-Ting Yeh
- Kai-Chun Jhan
- Shih-Kuo Chen