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Showing 51–100 of 145 results

Advanced filters: Author: X Y Guan Clear advanced filters

Cryo-EM structure of an amyloid fibril formed by full-length human prion protein

A cryo-EM structure of amyloid fibrils formed in vitro with recombinant human PrP provides insights into fibril architecture and the potential role of disease mutations.

Li-Qiang Wang
Kun Zhao
Yi Liang
Research08 Jun 2020
Nature Structural & Molecular Biology

Volume: 27, P: 598-602
Metalloradical approach for concurrent control in intermolecular radical allylic C−H amination

Controlling various selectivities in radical reactions presents both formidable challenges and great opportunities. Now, Co(II)-based metalloradical catalysis has enabled the concurrent control of multiple convergences and selectivities in intermolecular radical allylic C−H amination. The reaction provides access to valuable chiral α-tertiary amines directly from an isomeric mixture of alkenes.

Pan Xu
Jingjing Xie
X. Peter Zhang
Research12 Jan 2023
Nature Chemistry

Volume: 15, P: 498-507
Analysis of the Relationship of Insulin-Like Growth Factor-1 to the Growth Velocity and Feeding of Healthy Infants

X Wang
J Qi
Y Guan
Research01 Nov 2011
Pediatric Research

Volume: 70, P: 358
A LATS biosensor screen identifies VEGFR as a regulator of the Hippo pathway in angiogenesis

The Hippo pathway is a major orchestrator of organ development and homeostasis. Here Azad and colleagues develop a biosensor to monitor the activity of the Hippo pathway component LATS and identify VEGF signalling as an upstream regulator of LATS, supporting a role for Hippo signalling during angiogenesis.

T. Azad
H. J. Janse van Rensburg
X. Yang
ResearchOpen Access13 Mar 2018
Nature Communications

Volume: 9, P: 1-15
A remnant planetary core in the hot-Neptune desert

Observations of TOI-849b reveal a radius smaller than Neptune’s but a large mass of about 40 Earth masses, indicating that the planet is the remnant core of a gas giant.

David J. Armstrong
Théo A. Lopez
Zhuchang Zhan
Research01 Jul 2020
Nature

Volume: 583, P: 39-42
Signal transduction, cell cycle regulatory, and anti-apoptotic pathways regulated by IL-3 in hematopoietic cells: possible sites for intervention with anti-neoplastic drugs

WL Blalock
C Weinstein-Oppenheimer
JA McCubrey
Reviews09 Aug 1999
Leukemia

Volume: 13, P: 1109-1166
Dysfunctional ERG signaling drives pulmonary vascular aging and persistent fibrosis

Vascular dysfunction is associated with ageing and chronic diseases, but its role in lung repair and fibrosis is unclear. Here, the authors show that the endothelial transcription factor ERG is a mediator of vascular repair whose function declines in aged lungs resulting in sustained fibrosis

Nunzia Caporarello
Jisu Lee
Giovanni Ligresti
ResearchOpen Access25 Jul 2022
Nature Communications

Volume: 13, P: 1-19
25-years Trends and Risk factors related to Surgical Outcomes of Giant Retinal Tear-Rhegmatogenous Retinal Detachments

Daniel S. W. Ting
Valencia H. X. Foo
Shu Yen Lee
ResearchOpen Access25 Mar 2020
Scientific Reports

Volume: 10, P: 1-8
Strongly correlated perovskite fuel cells

A fundamentally different approach to designing solid oxide electrolytes is presented, using a phase transition to suppress electronic conduction in a correlated perovskite nickelate; this yields ionic conductivity comparable to the best-performing solid electrolytes in the same temperature range.

You Zhou
Xiaofei Guan
Shriram Ramanathan
Research16 May 2016
Nature

Volume: 534, P: 231-234
Dual-polarity metamaterial circular polarizer based on giant extrinsic chirality

J. H. Shi
Q. C. Shi
T. J. Cui
ResearchOpen Access12 Nov 2015
Scientific Reports

Volume: 5, P: 1-7
Author Correction: A detailed map of Higgs boson interactions by the ATLAS experiment ten years after the discovery

G. Aad
B. Abbott
L. Zwalinski
Amendments and CorrectionsOpen Access18 Oct 2023
Nature

Volume: 623, P: E5
Power-law relationship in the long-tailed sections of proton dose distributions

Bo Jiang
Xiaochun Wang
Xiaodong Zhang
ResearchOpen Access10 Jul 2018
Scientific Reports

Volume: 8, P: 1-9
Spatial mapping of the biologic effectiveness of scanned particle beams: towards biologically optimized particle therapy

Fada Guan
Lawrence Bronk
David R. Grosshans
ResearchOpen Access18 May 2015
Scientific Reports

Volume: 5, P: 1-10
Deforestation-induced warming over tropical mountain regions regulated by elevation

Deforestation causes elevation-dependent warming over tropical mountain regions, according to high-resolution climate simulations.

Zhenzhong Zeng
Dashan Wang
Eric F. Wood
Research14 Dec 2020
Nature Geoscience

Volume: 14, P: 23-29
Oscillating features in the electromagnetic structure of the neutron

Form factors encode the structure of nucleons. Measurements from electron–positron annihilation at BESIII reveal an oscillating behaviour of the neutron electromagnetic form factor, and clarify a long-standing photon–nucleon interaction puzzle.

M. Ablikim
M. N. Achasov
J. H. Zou
Research08 Nov 2021
Nature Physics

Volume: 17, P: 1200-1204
Association analysis of the dopamine D4 gene exon III VNTR and heroin abuse in Chinese subjects

T Li
K Xu
D A Collier
Research01 Sept 1997
Molecular Psychiatry

Volume: 2, P: 413-416
Site-specific proteasome phosphorylation controls cell proliferation and tumorigenesis

Dixon and colleagues and Guo and colleagues find that phosphorylation of the 19S proteasome subunit Rpt3 by DYRK2 increases proteasome activity and promotes cell proliferation, whereas loss of Rpt3 phosphorylation inhibits tumour formation in mice.

Xing Guo
Xiaorong Wang
Jack E. Dixon
Research14 Dec 2015
Nature Cell Biology

Volume: 18, P: 202-212
High-level expression of Rad51 is an independent prognostic marker of survival in non-small-cell lung cancer patients

G-B Qiao
Y-L Wu
H-W Stuerzbecher
ResearchOpen Access14 Jun 2005
British Journal of Cancer

Volume: 93, P: 137-143
A genome-wide association study identifies two new lung cancer susceptibility loci at 13q12.12 and 22q12.2 in Han Chinese

Hongbing Shen and colleagues report a genome-wide association study for lung cancer in individuals of Han Chinese ancestry. The authors identify two new lung cancer susceptibility loci.

Zhibin Hu
Chen Wu
Hongbing Shen
Research03 Jul 2011
Nature Genetics

Volume: 43, P: 792-796
Dynamic landscape and regulation of RNA editing in mammals

Using the GTEx data and others, a comprehensive analysis of adenosine-to-inosine RNA editing in mammals is presented; targets of the various ADAR enzymes are identified, as are several potential regulators of editing, such as AIMP2.

Meng How Tan
Qin Li
Jin Billy Li
Research12 Oct 2017
Nature

Volume: 550, P: 249-254
X-ray computed tomography datasets for forensic analysis of vertebrate fossils

Timothy B. Rowe
Zhe-Xi Luo
Matthew W. Colbert
ResearchOpen Access07 Jun 2016
Scientific Data

Volume: 3, P: 1-25
Methylation-induced silencing of ASC and the effect of expressed ASC on p53-mediated chemosensitivity in colorectal cancer

T Ohtsuka
X-F Liu
K Miyazaki
Research12 Dec 2005
Oncogene

Volume: 25, P: 1807-1811
Expression of barley SUSIBA2 transcription factor yields high-starch low-methane rice

Expression of a barley transcription factor SUSIBA2 in rice generates a plant with high-starch content and low-methane emissions by conferring a shift in the carbon flux that favours the allocation of photosynthates to aboveground biomass rather than to the roots.

J. Su
C. Hu
C. Sun
Research22 Jul 2015
Nature

Volume: 523, P: 602-606
Crystal structure of an antigenic outer-membrane protein from Salmonella Typhi suggests a potential antigenic loop and an efflux mechanism

Hong-Hsiang Guan
Masato Yoshimura
Chun-Jung Chen
ResearchOpen Access13 Nov 2015
Scientific Reports

Volume: 5, P: 1-12
Association analyses identify multiple new lung cancer susceptibility loci and their interactions with smoking in the Chinese population

Hongbing Shen and colleagues identify three new susceptibility loci for lung cancer in the Chinese population. Their follow-up analyses suggest that two of these loci interact multiplicatively with smoking dose to influence lung cancer risk.

Jing Dong
Zhibin Hu
Hongbing Shen
Research15 Jul 2012
Nature Genetics

Volume: 44, P: 895-899
A super-Earth and two sub-Neptunes transiting the nearby and quiet M dwarf TOI-270

The Transiting Exoplanet Survey Satellite (TESS) has identified a nearby, bright, quiescent M dwarf star that hosts two sub-Neptune-sized planets and one super-Earth-sized planet. The system is eminently suitable for follow-up studies of transit timing variations, radial velocity measurements and transmission spectroscopy.

Maximilian N. Günther
Francisco J. Pozuelos
Ian A. Waite
Research29 Jul 2019
Nature Astronomy

Volume: 3, P: 1099-1108
Publisher Correction: A super-Earth and two sub-Neptunes transiting the nearby and quiet M dwarf TOI-270

Maximilian N. Günther
Francisco J. Pozuelos
Ian A. Waite
Amendments and Corrections15 Aug 2019
Nature Astronomy

Volume: 3, P: 1157-1158
EIF5A2 predicts outcome in localised invasive bladder cancer and promotes bladder cancer cell aggressiveness in vitro and in vivo

J-H Wei
J-Z Cao
J-H Luo
ResearchOpen Access06 Feb 2014
British Journal of Cancer

Volume: 110, P: 1767-1777
Familial aggregation of lung cancer in a high incidence area in China

Y T Jin
Y C Xu
X Z He
ResearchOpen Access08 Mar 2005
British Journal of Cancer

Volume: 92, P: 1321-1325
Chloroplastic biosynthesis of melatonin and its involvement in protection of plants from salt stress

Xiaodong Zheng
Dun X. Tan
Jin Kong
ResearchOpen Access01 Feb 2017
Scientific Reports

Volume: 7, P: 1-12
p120Ras-GAP binds the DLC1 Rho-GAP tumor suppressor protein and inhibits its RhoA GTPase and growth-suppressing activities

X-Y Yang
M Guan
N C Popescu
Research19 Jan 2009
Oncogene

Volume: 28, P: 1401-1409
Comparative analyses of multi-species sequences from targeted genomic regions

J. W. Thomas
J. W. Touchman
E. D. Green
Research14 Aug 2003
Nature

Volume: 424, P: 788-793
Characterization of tumor suppressive function of P300/CBP-associated factor at frequently deleted region 3p24 in esophageal squamous cell carcinoma

C Zhu
Y-R Qin
X-Y Guan
Research15 Jun 2009
Oncogene

Volume: 28, P: 2821-2828
Hippocampal cells segregate positive and negative engrams

The hippocampus contains neurons that correspond to two partially non-overlapping sets of positive and negative engrams, which may be distinguished by molecular, cellular, and projection-specific features.

Monika Shpokayte
Olivia McKissick
Steve Ramirez
ResearchOpen Access26 Sept 2022
Communications Biology

Volume: 5, P: 1-15
A phase III randomised controlled trial of erlotinib vs gefitinib in advanced non-small cell lung cancer with EGFR mutations

J J Yang
Q Zhou
Y L Wu
ResearchOpen Access19 Jan 2017
British Journal of Cancer

Volume: 116, P: 568-574
ΔNp73α regulates MDR1 expression by inhibiting p53 function

A Vilgelm
J X Wei
A Zaika
Research22 Oct 2007
Oncogene

Volume: 27, P: 2170-2176
Inhibition of ATG12-mediated autophagy by miR-214 enhances radiosensitivity in colorectal cancer

J. L. Hu
G. Y. He
L. Liang
ResearchOpen Access20 Feb 2018
Oncogenesis

Volume: 7, P: 1-12
Prognostic model for survival of local recurrent nasopharyngeal carcinoma with intensity-modulated radiotherapy

Y-M Tian
Y-H Tian
F Han
ResearchOpen Access12 Dec 2013
British Journal of Cancer

Volume: 110, P: 297-303
Estrogen/ERR-α signaling axis is associated with fiber-type conversion of upper airway muscles in patients with obstructive sleep apnea hypopnea syndrome

H. H. Chen
J. Lu
X. P. Li
ResearchOpen Access02 Jun 2016
Scientific Reports

Volume: 6, P: 1-11
Predictors for misreporting sodium and potassium intakes by overweight and obese participants in a food-based clinical trial: implications for practice

Vivienne X. Guan
Yasmine C. Probst
Linda C. Tapsell
Research10 Aug 2018
European Journal of Clinical Nutrition

Volume: 74, P: 203-207
Motor unit number estimation of the tibialis anterior muscle in spinal cord injury

G-X Xiong
J-W Zhang
H Guan
Research11 Mar 2008
Spinal Cord

Volume: 46, P: 696-702
Motor unit number estimation may be a useful method to evaluate motor function recovery after spinal cord transection in rats

G-X Xiong
Y Guan
H Guan
Research03 Nov 2009
Spinal Cord

Volume: 48, P: 363-366
Acetylcholinesterase expression mediated by c-Jun-NH2-terminal kinase pathway during anticancer drug-induced apoptosis

R Deng
W Li
X-F Zhu
Research22 May 2006
Oncogene

Volume: 25, P: 7070-7077
Clusterin plays an important role in hepatocellular carcinoma metastasis

S H Lau
J S T Sham
X-Y Guan
Research17 Oct 2005
Oncogene

Volume: 25, P: 1242-1250
Effect of folic acid intervention on ALT concentration in hypertensives without known hepatic disease: a randomized, double-blind, controlled trial

X Qin
J Li
Y Huo
Research16 Nov 2011
European Journal of Clinical Nutrition

Volume: 66, P: 541-548
Association of long non-coding RNA H19 and microRNA-21 expression with the biological features and prognosis of non-small cell lung cancer

Y Zhou
B Sheng
Y Zhang
Research11 Aug 2017
Cancer Gene Therapy

Volume: 24, P: 317-324
Ligand-dependent ubiquitination of Smad3 is regulated by casein kinase 1 gamma 2, an inhibitor of TGF-β signaling

X Guo
D S Waddell
X-F Wang
Research15 Sept 2008
Oncogene

Volume: 27, P: 7235-7247
Correlation between diffusion tensor imaging parameters and clinical assessments in patients with cervical spondylotic myelopathy with and without high signal intensity

Y Liu
C Kong
X Chen
Research05 Sept 2017
Spinal Cord

Volume: 55, P: 1079-1083
Proline-rich tyrosine kinase 2 and its phosphorylated form pY881 are novel prognostic markers for non-small-cell lung cancer progression and patients’ overall survival

B-H Kuang
M-Q Zhang
X Zhang
ResearchOpen Access06 Aug 2013
British Journal of Cancer

Volume: 109, P: 1252-1263
Expression of cytoplasmic and nuclear Survivin in primary and secondary human glioblastoma

D Xie
Y X Zeng
X Y Guan
ResearchOpen Access13 Dec 2005
British Journal of Cancer

Volume: 94, P: 108-114

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