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Authors find room-temperature ferroelectricity in single element Te nanowires, highlighting that reducing dimensions to 1D in low-dimensional piezoelectric materials with chain structures is an effective strategy to induce ferroelectricity absent in their 2D form.

The use of a needle-shaped optical beam improves the depth of field for photoacoustic imaging.

The Cryo-EM structures reported in this work reveal how heparin incorporates into α-syn fibril formation to determine fibril polymorphs. This highlights the role of biological polymers in the conformational selection and neuropathological regulation of amyloid fibrils.

Analysis of a set of 1,863 bursts from the repeating source FRB 20201124A provides evidence of a complicated magnetized site within about an astronomical unit from the source in a barred galaxy.

The authors demonstrate ultrafast symmetry breaking by optically driven photocurrents.

Ice cores are unique climate archives, but their dating can be challenging. Here, the authors have realized a method for counting ⁸¹Kr atoms in 1-kg polar ice-core samples, enabling access to climate information of the past million years in deep ice.

The measurement of the total cross-section of proton–proton collisions is of fundamental importance for particle physics. Here, the first measurement of the inelastic cross-section is presented for proton–proton collisions at an energy of 7 teraelectronvolts using the ATLAS detector at the Large Hadron Collider.

The miR396–GRF module controls a trade-off between competence and speed during root tip regeneration in Arabidopsis. Roots ectopically expressing miR396 grow without stem cell niche reconstitution, probably due to dispersed stem cell activity.

This study provides evidence for a continental-scale river system that existed in eastern Tibet before the India-Asia collision. The river system developed an extensive low-relief landscape, which was uplifted and dissected during the late Cenozoic.

The E46K α-synuclein mutation causes familial Parkinson’s disease. Here, the authors present the cryo-EM structure of N-terminally acetylated E46K α-synuclein fibrils and find that it is distinct from other known α-synuclein fibril structures.

The interaction between antiferromagnetic magnons and electrons sits at the heart of many strongly correlated systems, however, investigation has been hampered by a lack of clear-cut examples. Here, Yu et al directly observe a kink in the dispersion, a result of renormalization due to the electron-antiferromagnetic magnon interaction.

Complexities of laser-material interactions pose a challenge to minimize defects in additively manufactured metal parts. Here the authors visualize all phases of matter simultaneously to expand understanding of the interactions and show atmospheric information can characterize process stability.

The cleavage of C–C bonds in hydrocarbons is traditionally entrusted to precious metal catalysts, whereas common non-reducible oxides are considered unreactive. Now, the authors report nanostructured silica-embedded zirconia nanoparticles that are competent for the hydrogenolysis of polyethylene with remarkable performance.

Quantum simulators should be able to give insight on exotic physics models such as supersymmetric extensions of Standard Model. Here, the authors demonstrate a first step in this direction, realising a prototypical SUSY model (and spontaneous SUSY breaking within it) using a trapped ion quantum simulator.

A strategy that combines freeze-casting and salting-out treatments produces strong, tough, stretchable and fatigue-resistant poly(vinyl alcohol) hydrogels.

Ferroelectric field-effect transistors based on molybdenum disulfide can be used to build an in-memory sparsity architecture in which index memory is moved next to individual synapses, creating a sparse neural network without external memory indexing.

Measurements of the proton’s spin structure in experiments scattering a polarized electron beam off polarized protons in regions of low momentum transfer squared test predictions from chiral effective field theory of the strong interaction.

Mylonas et al. demonstrate the feasibility of using deep learning for markerless prostate segmentation in kilovoltage x-ray images during radiation therapy. This proof-of-principle retrospective study, involving 30 patient treatments, highlights the potential for real-time image guidance without implanted markers or additional hardware.

A comparison of two complete sets of human centromeres reveals that the centromeres show at least a 4.1-fold increase in single-nucleotide variation compared with their unique flanks, and up to 3-fold variation in size, resulting from an accelerated mutation rate.

There are multiple ways by which energy and charge transfer occur in weakly bound systems. Here the authors reveal a heavy ion N⁺ transfer in a doubly charged Van der Waals cluster produced in collisions of the highly charged Ne⁸⁺ ion with N₂Ar, leading to fragmentation of N⁺ and NAr⁺ via Coulomb explosion.

Lithium–oxygen batteries are expected to have high-energy density, assuming that anodic lithium is fully reversible upon cycling. Shui et al. disprove this assumption by monitoring the changes of anode composition and morphology, and reveal the loss mechanism and transport paths of lithium ions.

Caloric restriction is a common approach to weight reduction, however, weight regain is common. Here the authors report that caloric restriction reduces the abundance of Parabacteroides distasonis in the gut and alters serum bile acid (BA) profile, which contribute to weight regain in mice.

The flagship paper of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium describes the generation of the integrative analyses of 2,658 cancer whole genomes and their matching normal tissues across 38 tumour types, the structures for international data sharing and standardized analyses, and the main scientific findings from across the consortium studies.

It remains an open question as to whether the quantum spin liquid state survives material disorder, or is replaced by some spin-liquid like state. Here, Rao et al succeed in resolving a resolving a κ₀/T residual in the thermal conductivity of YbMgGaO₄ strongly suggesting the survival of the quantum spin liquid state.

Some cancer patients first present with metastases where the location of the primary is unidentified; these are difficult to treat. In this study, using machine learning, the authors develop a method to determine the tissue of origin of a cancer based on whole sequencing data.

Perovskite light emitting diodes suffer from operational stability, showing rapid decay of performance within minutes to hours after turn-on. Here, the authors investigate how the steric and Coulomb interaction of ammonium passivation molecules with varying alkyl chain length can improve device stability by suppressing iodide ion migration.

In order to optimize thermoelectric (TE) materials which are used to convert thermal energy and electrical energy, the underlying physics needs to be understood. Here, the authors show that by exploiting static local structure distortion, transverse acoustic phonons can be suppressed resulting in high performing TE materials.

The authors study CsV₃Sb₅ by nuclear quadrupole resonance. At ambient pressure, there are two superconducting gaps with line nodes in the smaller one. For pressures above P_c ~ 1.85 GPa, where the charge-density wave phase is completely suppressed, they observe fully-gapped superconductivity with broken rotational symmetry.

G protein-coupled receptors are a large family of signalling proteins that mediate cellular responses primarily via G proteins or arrestins, and they are targets of one-third of the current clinically used drugs; here, an active form of human rhodopsin bound to a pre-activated form of the mouse visual arrestin-1 is determined, revealing unique structural features that may constitute essential elements for arrestin-biased signalling.

The battery performance at the cell level is an integration of contributions from many active particles. Here, the authors present a direct visualization of the active cathode particles that react heterogeneously and asynchronously by using coherent multi-crystal diffraction and optical microscopy.

High-precision photoemission measurements determine that the superconducting pairing symmetry in KFe₂As₂ is the same as in other types of iron-based superconductors, despite having different features in the band structure.

Zhu and colleagues show that a subpopulation of spleen-derived fibroblasts secrete Gremlin 1, which suppresses chronic myeloid leukemia progression by inducing leukemia stem cell apoptosis through the BMP signaling pathway.

The voltage-gated sodium channel Na_v1.7 has a dual role in osteoarthritis—in chondrocytes, it promotes joint damage, and in dorsal root ganglia neurons, it increases pain transmission.

Measurements of the proton’s generalized spin polarizabilities provide discriminating power between effective descriptions of the strong interaction at low energy.

Diffractive imaging of an important class of battery electrodes during cycling shows that lattice strain is a crucial yet overlooked factor that contributes to voltage fade over time.

A machine-learning pipeline that mines the entire space of polypeptide-chain sequences can identify potent antimicrobial peptides by integrating tasks that gradually narrow down the search space.

Identifying scaling laws in metal 3D printing is key to process optimization and materials development. Here the authors report scaling laws to quantify correlation between process parameters, keyhole stability and pore formation by high-speed synchrotron X-ray imaging and multiphysics modeling.

The decay asymmetry and helicity phase of polarized baryon–antibaryon pairs are measured at the BESIII experiment, testing charge–parity symmetry and revealing a discrepancy of the Λ → pπ⁻ decay asymmetry with respect to the current world average.

At the Relativistic Heavy Ion Collider, observations of two meson species produced by heavy-ion collisions, ϕ and K^*0, show surprising patterns of global spin alignment, being unexpectedly large and consistent with zero, respectively.

Charge–density–wave correlations, quantum oscillations and Fermi-liquid charge transport are at the centre of a heated debate in cuprate superconductivity. Using resonant X-ray scattering, Tabis et al. investigate the charge order and its link to the electronic transport properties in HgBa₂CuO_4+δ.

An ideal topological insulator possesses an insulating bulk and a unique conducting surface however such behaviour is typically inhibited by bulk conduction due to defects. Here, the authors show that Sn-doped Bi_1.1Sb_0.9Te₂S grown by the vertical Bridgman technique might overcome this hurdle.

Highly stretchable organic electrochemical transistors with stable charge transport under severe tensional strains are demonstrated using a honeycomb semiconducting polymer morphology, thereby enabling controllable signal output for diverse stretchable bioelectronic applications.

Placenta accreta spectrum (PAS) is a high-risk obstetrical complication associated with significant morbidity and mortality. Here the authors discover a uniquely high prevalence of circulating trophoblasts clusters in PAS and explore their diagnostic potential to augment current diagnostic modalities for the early detection of PAS.

How superconductivity emerges out of the antiferromagnetic insulating state of the cuprates is unclear. High-resolution ARPES measurements reported by Zhouet al.suggest that this emerges at the point where antiferromagnetic order disappears and the nodal gap of its electronic structure falls to zero.

Agarwal et al. and Wang et al. show that vesicle-associated membrane protein 2 (VAMP2) interacts with and regulates alpha-synuclein biomolecular condensation, affecting α-synuclein function, which may prevent pathological amyloid aggregation.

Viral pathogen load in cancer genomes is estimated through analysis of sequencing data from 2,656 tumors across 35 cancer types using multiple pathogen-detection pipelines, identifying viruses in 382 genomic and 68 transcriptome datasets.

CuP2 has a puzzling thermal transport behavior, with low thermal conductivity but quite large mean sound speeds. Here, the authors conduct a systematical study of the atomic structure and lattice dynamics of CuP2 to reveal the origin, finding a dimer rattling behavior.

In this study the authors consider the structural variants (SVs) present within cancer cases of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium. They report hundreds of genes, including known cancer-associated genes for which the nearby presence of a SV breakpoint is associated with altered expression.

Bi et al. reveal a coordinated function for GATA3 and AP1 in altering enhancer landscapes, thereby promoting a basal/mesenchymal phenotype and endocrine resistance in breast cancer.