Biologic agents have been used successfully to treat rheumatoid arthritis, but are less effective in osteoarthritis. Chevalier et al. discuss the use of cytokine blockers, inhibitors of nitrogen oxide production, and growth factors to treat osteoarthritis—clinical trial data has been overwhelmingly negative but glimmers of hope still exist.
- Xavier Chevalier
- Florent Eymard
- Pascal Richette
