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Nature Cell Biology (1)

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Advanced filters: Author: Xavier Deschênes-Simard Clear advanced filters

Senescence-associated ribosome biogenesis defects contributes to cell cycle arrest through the Rb pathway

Lassard et al. demonstrate a relationship between cellular senescence and perturbed ribosome biogenesis and find that the ribosomal protein S14 is an inhibitor of CDK4, inducing an Rb-dependent cell cycle arrest.

Frédéric Lessard
Sebastian Igelmann
Gerardo Ferbeyre
Research25 Jun 2018
Nature Cell Biology

Volume: 20, P: 789-799

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Senescence-associated ribosome biogenesis defects contributes to cell cycle arrest through the Rb pathway

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