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Showing 1–5 of 5 results
Advanced filters: Author: Xavier Rovira-Clavé Clear advanced filters

  • Emerging high-plex imaging technologies are limited in resolving subcellular biomolecular features. Here, the authors propose a spatial histopathology tool that allows for high-plex protein staining and physical expansion, while retaining the lateral tissue expansion.

    • Yunhao Bai
    • Bokai Zhu
    • Sizun Jiang
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-18

  • The interaction between the host immune response and the component organisms forming the microbiota is critical during homeostatic but all pathological contexts. Here the authors use a multi-omics spatial approach to dissect and characterise host and microbiome in a murine model of intestinal inflammation.

    • Bokai Zhu
    • Yunhao Bai
    • Sizun Jiang
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-20

  • Secondary ion beam mass spectrometry (SIMS) is a method to obtain a chemical snapshot of biological tissue, but the spatial resolution is low. Here, the authors develop a computational and technology pipeline to localise a chemical signal in SIMS in 3D and sub-25 nm accuracy, called Ion Beam Tomography

    • Ahmet F. Coskun
    • Guojun Han
    • Garry P. Nolan
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-19