Nature Search

Gastric MALT lymphoma: a model of chronic inflammation-induced tumor development

Gastric mucosa-associated lymphoid tissue (MALT) lymphoma pathogenesis is associated withHelicobacter pyloriinfection and genetic aberrations involving the nuclear factor κB signaling pathway. In this Review, gastric MALT lymphoma is presented an outstanding example of the close pathogenetic link between chronic inflammation and tumor development.

Xavier Sagaert
Eric Van Cutsem
Thomas Tousseyn
Reviews04 May 2010
Nature Reviews Gastroenterology & Hepatology

Volume: 7, P: 336-346
Homeobox NKX2-3 promotes marginal-zone lymphomagenesis by activating B-cell receptor signalling and shaping lymphocyte dynamics

The homeobox NKX2 family of transcriptional factors has been shown to regulate fundamental developmental processes. Here, the authors show that NKX2-3 is a bona fideoncogenic driver in marginal-zone B-cell lymphoma and that it promotes lymphomagenesis by shaping lymphocyte dynamics and promoting BCR signalling.

Eloy F. Robles
Maria Mena-Varas
Jose A. Martinez-Climent
ResearchOpen Access14 Jun 2016
Nature Communications

Volume: 7, P: 1-16
The pathogenesis of MALT lymphomas: where do we stand?

X Sagaert
C De Wolf-Peeters
M Baens
Reviews18 Jan 2007
Leukemia

Volume: 21, P: 389-396
MALT1 and BCL10 aberrations in MALT lymphomas and their effect on the expression of BCL10 in the tumour cells

Xavier Sagaert
Michael Laurent
Christiane De Wolf-Peeters
Research02 Dec 2005
Modern Pathology

Volume: 19, P: 225-232
Single cell dynamics of tumor specificity vs bystander activity in CD8⁺ T cells define the diverse immune landscapes in colorectal cancer

Daniel Morales Borràs
Sara Verbandt
Abhishek D. Garg
ResearchOpen Access15 Nov 2023
Cell Discovery

Volume: 9, P: 1-30
Comparative expressed sequence hybridization studies of t(11;18)(q21;q21)-positive and -negative gastric MALT lymphomas reveal both unique and overlapping gene programs

Xavier Sagaert
Thomas Tousseyn
Christiane De Wolf-Peeters
Research15 Jan 2010
Modern Pathology

Volume: 23, P: 458-469
Expression profiling of budding cells in colorectal cancer reveals an EMT-like phenotype and molecular subtype switching

Linde De Smedt
Sofie Palmans
Xavier Sagaert
ResearchOpen Access24 Nov 2016
British Journal of Cancer

Volume: 116, P: 58-65
Other immunomodulatory agent-related lymphoproliferative diseases: a single-center series of 72 biopsy-confirmed cases

Lukas Marcelis
Charlien Berghen
Thomas Tousseyn
Research15 May 2018
Modern Pathology

Volume: 31, P: 1457-1469
The dynamics of the B follicle: understanding the normal counterpart of B-cell-derived malignancies

X Sagaert
B Sprangers
C De Wolf-Peeters
Reviews10 May 2007
Leukemia

Volume: 21, P: 1378-1386
Microsatellite instable vs stable colon carcinomas: analysis of tumour heterogeneity, inflammation and angiogenesis

L De Smedt
J Lemahieu
X Sagaert
ResearchOpen Access11 Jun 2015
British Journal of Cancer

Volume: 113, P: 500-509
Evaluation of efficacy and safety markers in a phase II study of metastatic colorectal cancer treated with aflibercept in the first-line setting

Diether Lambrechts
Bernard Thienpont
Eric Van Cutsem
ResearchOpen Access10 Sept 2015
British Journal of Cancer

Volume: 113, P: 1027-1034

Search

Gastric MALT lymphoma: a model of chronic inflammation-induced tumor development

Homeobox NKX2-3 promotes marginal-zone lymphomagenesis by activating B-cell receptor signalling and shaping lymphocyte dynamics

The pathogenesis of MALT lymphomas: where do we stand?

MALT1 and BCL10 aberrations in MALT lymphomas and their effect on the expression of BCL10 in the tumour cells

Single cell dynamics of tumor specificity vs bystander activity in CD8⁺ T cells define the diverse immune landscapes in colorectal cancer

Comparative expressed sequence hybridization studies of t(11;18)(q21;q21)-positive and -negative gastric MALT lymphomas reveal both unique and overlapping gene programs

Expression profiling of budding cells in colorectal cancer reveals an EMT-like phenotype and molecular subtype switching

Other immunomodulatory agent-related lymphoproliferative diseases: a single-center series of 72 biopsy-confirmed cases

The dynamics of the B follicle: understanding the normal counterpart of B-cell-derived malignancies

Microsatellite instable vs stable colon carcinomas: analysis of tumour heterogeneity, inflammation and angiogenesis

Evaluation of efficacy and safety markers in a phase II study of metastatic colorectal cancer treated with aflibercept in the first-line setting

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