Kanakaraju Kaliannan et al. show that converting omega-6 polyunsaturated fatty acids (n-6 PUFA) to omega-3 polyunsaturated fatty acids (n-3 PUFA) improves overall metabolism in mice, lowering risks for liver cancer. This study suggests the importance of keeping the tissue level of n-3 PUFA comparable to that of n-6 PUFA in preventing metabolic diseases.
- Kanakaraju Kaliannan
- Xiang-Yong Li
- Jing X. Kang